An orally administered aqueous suspension comprises microcapsules (MC's), each having a core of amoxicillin (A) coated with a release-controlling film (I). (I) consists of (a) film-forming, water-insoluble cellulose derivative, nitrogen-containing polymer and/or plasticizer; (b) hydrophilic polymer; or (c) film-forming polymer, water-soluble polymer, plasticizer and optionally surfactant and/or lubricant. In an orally administered aqueous suspension of MC's, each MC comprises a core of amoxicillin (A) coated with a release-controlling film (I) such that the liquid phase is (or becomes) saturated with (A) in contact with the MC's. (I) consists of : (a) components comprising; (i) film-forming polymer(s) (P1) insoluble in gastro-intestinal fluids, selected from water-insoluble cellulose derivative(s), forming 50-80 (preferably 50-80) wt. % of (I); (ii) nitrogen-containing polymer(s) (P2) selected from polyacrylamide, poly-N-vinyl-amide and/or poly-N-vinyl-lactam, forming 2-20 (preferably 4-15) wt. % of (I); (iii) plasticizer(s) selected from glycerol esters, phthalates, citrates, sebacates, cetyl alcohol esters and castor oil, forming 2-20 (preferably 4-15) wt. % of (I); and (iv) one or more of anionic and/or nonionic surfactants and/or lubricants, forming 2-20 (preferably 4-15) wt. % of (I); (b) components comprising; (i) hydrophilic polymer(s) carrying groups ionized at neutral pH (preferably cellulose derivatives); and (ii) hydrophobic compound(s) (other than (a)); or optionally (c) components comprising; (i) film-forming polymer(s) (P1) insoluble in gastro-intestinal fluids; (ii) water-soluble polymer(s); (iii) plasticizer(s); and (iv) surfactant(s) and/or lubricant(s) (preferably anionic and/or nonionic surfactants). Independent claims are included for: (1) a medicament comprising a suspension as above; and (2) a medicament comprising a kit for the production of a suspension as above, comprising the (A)-containing MC's, optionally (A) in immediate release (non-coated) form and the liquid phase (or at least some of its ingredients and/or instructions for its preparation).
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