Device to measure influence of physical, biological, and/or chemical stress on sample, or vice-versa comprises sample of reconstructed skin; and detection system that is at least partially in contact with sample and/or with culture device

摘要

A device (1) comprises a sample of reconstructed tissue (4) (e.g. skin); and a detection system that is at least partially in contact with the sample and/or with a device (2, 3) serving to culture the sample, and configured to measure the influence of a physical, biological, and/or chemical stress on at least a fraction of sample, or vice-versa, where the detection system includes a sensor (20) and/or stress-imparting unit (30) in contact with sample and/or with culture device. An independent claim is also included for manufacturing the device, where at least part of the detection system is implanted in tissue that is completely reconstructed and viable.