Preparing spheroids, useful e.g. in dietetics, comprises mixing active ingredient of vegetable origin, solution of vegetable origin with active ingredient and absorbing and adsorbent substances, wetting, extruding and spheronizing

摘要

Preparation (M1) of spheroids (I) comprises mixing an active ingredient (Ia) of vegetable origin in an isolated form, a solution (II) of vegetable origin containing (Ia) or its precursor, and an absorbing substance (Ib) and adsorbent substance (Ic) with plastic properties compatible with the process; wetting the mixture by a moisturizing liquid; extruding the wet mixture; and forming (I) by spheronization of the extruded product. Independent claims are also included for the following: (1) spheroids (I) prepared by (M1); and (2) a medicament composition comprising (Ia) in a galenic form of (I). ACTIVITY : Anabolic. MECHANISM OF ACTION : None given.