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Characterization and isolation of subsets of human embryonic stem cells (HES) and cells associated or derived therefrom
Characterization and isolation of subsets of human embryonic stem cells (HES) and cells associated or derived therefrom
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机译:人胚胎干细胞(HES)子集以及与之相关或衍生的细胞的表征和分离
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摘要
A sub-population of HES cells is identified which is positive for specific HES markers. These cell types are identified by expression of particular GCTM-2 antigens. A method based on the identification of GCTM-2 can differentiate between substantially undifferentiated or differentiated cell populations. Spontaneous differentiation often occurs in HES cultures resulting in non-homogeneous cell cultures. The invention also provides further sub populations of cells within differentiated cultures of HES cells that are SCL or epithelial in nature.
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