COMPOSITION FOR TREATING PROTEASOME INHIBITOR-RESISTANT CANCER, KIT FOR TREATMENT, AND SCREENING METHOD OF COMPOUND FOR TREATING PROTEASOME INHIBITOR-RESISTANT CANCER

摘要

PPROBLEM TO BE SOLVED: To provide a composition for treating a proteasome inhibitor-resistant cancer, a screening method thereof, or the like by way of precaution against appearance of a proteasome inhibitor-resistant cancer cell. PSOLUTION: The composition for treating the proteasome inhibitor-resistant cancer comprises as an effective ingredient fluorouracil, a prodrug thereof, or a salt thereof, or a topoisomerase inhibitor or a salt thereof. The screening method of the compound for treating the proteasome inhibitor-resistant cancer utilizes a cell caused to have acquired resistance to a proteasome inhibitor. PCOPYRIGHT: (C)2007,JPO&INPIT