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Phosphoglycerate mutase promoter and glyceraldehyde-3-phosphate dehydrogenase for gene expression in oleaginous yeast

机译:磷酸甘油酸突变酶启动子和3-磷酸甘油醛脱氢酶在油性酵母中的基因表达

摘要

Promoter region associated with alkane-assimilating yeast (Yarrowia lipolytica) glyceraldehyde-3-phosphate dehydrogenase and (gpd) phosphoglycerate mutase in (gpm) gene, effective for the expression of heterologous genes in oleaginous yeast especially It is has been found. The promoter regions of the present invention, to drive high-level expression of genes involved in production of ω-3 and ω-6 of fatty acids has been shown.
机译:已经发现与(gpm)基因中的与烷烃同化的酵母(解脂耶氏酵母(Yarrowia lipolytica))甘油醛-3-磷酸脱氢酶和(gpd)磷酸甘油酸变位酶相关的启动子区域,特别对于在油性酵母中表达异源基因有效。已经显示出本发明的启动子区域,其驱动与脂肪酸的ω-3和ω-6的产生有关的基因的高水平表达。

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