Promoter region associated with alkane-assimilating yeast (Yarrowia lipolytica) glyceraldehyde-3-phosphate dehydrogenase and (gpd) phosphoglycerate mutase in (gpm) gene, effective for the expression of heterologous genes in oleaginous yeast especially It is has been found. The promoter regions of the present invention, to drive high-level expression of genes involved in production of ω-3 and ω-6 of fatty acids has been shown.
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