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Novel polymorph of ondansetron, process for producing the polymorph, pharmaceutical composition containing the polymorph, and use of the polymorph as an antiemetic
Novel polymorph of ondansetron, process for producing the polymorph, pharmaceutical composition containing the polymorph, and use of the polymorph as an antiemetic
This invention relates to new polymorphs of (±)1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-il)methyl]-4H-carbazol-4-one, known under the INN of ondansetron, to processes for preparing said polymorphs, to pharmaceutical compositions containing them and to their use in the treatment and prophylaxis of nausea and vomiting. The invention provides new stable polymorphic forms of ondansetron and processes for manufacturing them at an industrial scale.
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