Technetium - and bis (heteroaryl) rhenium complex - bis (heteroaryl) complexes, as well as how to use them

摘要

Heteroaryl various ligands, for example, one aspect of the present invention, radiopharmaceuticals for therapeutic applications and clinical diagnostic applications as well as various complexes of the radionuclide and ligand pyridyl and imidazolyl ligands their use in. And form part of the complex described above, another aspect of the present invention relates to imidazolyl and pyridyl ligand ligand. It is also described for the preparation of radionuclide complexes. For conjugation to small peptides by solid phase synthesis, lysine derivatized, another aspect of the present invention is directed to pyridyl ligands and imidazolyl ligands based on the bis amino acid alanine. In addition, the present invention relates to a method for imaging a region of a mammal using the complexes of the present invention.