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Labeling synthesis method of ketone and amine carbon isotopes by Suzuki coupling reaction using carbon monoxide isotopes
Labeling synthesis method of ketone and amine carbon isotopes by Suzuki coupling reaction using carbon monoxide isotopes
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机译:一氧化碳同位素的铃木偶联反应标记酮和胺碳同位素的合成方法
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摘要
Methods and reagents for synthesizing carbon-isotope labeled ketones and amines by carbonylation via Suzuki coupling reaction using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled ketones and amines are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
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