The stabilization method or Grignard reagent solution

摘要

PROBLEM TO BE SOLVED: To obtain the subject stabilized solution capable of suppressing or preventing deposition of a precipitate or crystal by allowing a specific compound to coexist in a tetrahydrofuran (THF) solution of a Grignard reagent. ;SOLUTION: This solution comprises a THF solution of a Grignard reagent (pref. a 3-5C alkylmagnesium halide, e.g. n-propylmagnesium chloride) and an alkylene glycol ether (pref. monoethylene glycol dimethyl ether). It is preferable that THF is included at 2-12 molar times the Grignard reagent and that the alkylene glycol ether is included at 0.5-20 wt.% in the THF solution of the Grignard reagent. It is also preferable that the objective solution is prepared at a reaction temperature of room temperature to 100°C; wherein the reaction time is 10 h. The THF solution of the Grignard reagent is preferably prepared by successive addition of an organic halide to THF containing magnesium.;COPYRIGHT: (C)1999,JPO