AVIAN HERPESVIRUS-BASED LIVE RECOMBINANT AVIAN VACCINE, IN PARTICULAR AGAINST GUMBORO DISEASE

摘要

PPROBLEM TO BE SOLVED: To provide a recombinant live vaccine for avian use which are based on avian herpesvirus, in particular the Marek's disease virus (MDV) including HVT virus (herpesvirus of turkey), in which has been inserted, by genetic recombination, at least one nucleotide sequence which encodes and expresses an antigenic polypeptide of an avian pathogen efficiently protecting the vaccinated animal against the pathogen. PSOLUTION: The recombinant live virus of the Marek's disease virus (MVD) has a base sequence inserted in the UL43 gene under the control of the cytomegalovirus (CMV) immediate early (IE) promoter and encoding a polypeptide VP2 of IBDV virus. PCOPYRIGHT: (C)2007,JPO&INPIT