Method for producing osteogenesis promoter and method for producing osteogenic composition using osteogenesis promoter

摘要

An osteoinduction substance is extracted from animal bones and essentially comprises Mg, Si, Ca, and Na. The osteoinduction substance is manufactured by subjecting the animal bone to acid dipping, liming, neutralization, thermal extraction, condensation, and dehydration to obtain gelatin. The gelatin is then subjected to deproteinization under a nonheat or a low-temperature condition to extract the osteoinduction substance. The osteoinduction substance is mixed with at least one of hydroxyapatite powder and chitosan to form a bone filling material. When the osteoinduction substance is mixed with chitosan sol, a bone filling material of a sheet type is obtained. IMAGE