Leukocyte removal apparatus and method for preparing leukocyte removal preparation

摘要

PROBLEM TO BE SOLVED: To make it possible to maintain high white cell removability and to improve handling quality by providing the inside of the connecting tube on the downstream side of a white cell removing filter with a small-diameter part for flow velocity adjustment. SOLUTION: This white cell removing device is constituted by connecting a blood bag 7 and a recovering bag 7 to each other by intervening an introducing port 1, the white cell removing filter 2, a leading-out port 6, connecting pipes 3, 3', a meshed chamber 4 and a Robert clamp 5 therebetween. In such a case, the downstream side of the white cell removing filter 2 is provided with a small-diameter part A for flow velocity adjustment. The effective sectional area of this small-diameter part A for flow velocity adjustment is set at a range of about 0.1 to 5.0mm2 and the ratio of the length/effective sectional area thereof at about 3 to 400mm/mm2 . The small-diameter part A for flow velocity adjustment is formable of a hollow tube adapted to this size range. The bag-back filtration of, for example, a low-viscosity white cell-contg. liquid having a viscosity of about =5.5mPa.s is executable at a fall of about 5 to 2.0m without clogging, etc., by this constitution.