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Bridge is substituted with an aromatic amine of diagnostic imaging over nitrogen and sulfur donor atom ligands

机译:桥被氮和硫供体原子配体上诊断成像的芳香胺取代

摘要

(57) metal chelating compound is substituted with an aromatic amine of formula (I) (variables in the formula are as defined in claim), [Abstract] The present invention is prepared from the chelating compound chelate and chelate that - targeting moiety conjugates, and I to provide a process for the preparation of these compounds. Radionuclides such as 186/188 Re or 99m Tc thereof include metals which can be chelated by the chelating compound.
机译:(57)金属螯合化合物被式(I)的芳族胺取代(式中的变量如权利要求所定义),[摘要]本发明由该螯合化合物螯合和与-靶向部分缀合物螯合制备,我提供了制备这些化合物的方法。诸如 186/188 Re或 99m Tc的放射性核素包括可以被螯合化合物螯合的金属。

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