Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same

摘要

The multiphase combination preparation for oral therapy of dysfunctional uterine bleeding and for oral contraception contains a first phase of 2 daily dosage units, each consisting of 3 mg of estradiol valerate; a second phase of two groups of daily dosage units, which consist of a first group containing 5 daily dosage units, each of which consist of a combination of 2 mg of estradiol valerate and 2 mg of dienogest, and a second group containing 17 daily dosage units, each of which consist of a combination of 2 mg of estradiol valerate and 3 mg of dienogest; a third phase of 2 daily dosage units each consisting of 1 mg of estradiol valerate; and another phase of 2 daily dosage units of a pharmaceutically harmless placebo; so that the multiphase combination preparation consists of a total number of 28 daily dosage units.