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RNA expression profile predicting response to tamoxifen in breast cancer patients
RNA expression profile predicting response to tamoxifen in breast cancer patients
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机译:RNA表达谱预测乳腺癌患者对他莫昔芬的反应
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摘要
The present invention regards predicting a response to a therapy using RNA expression profiling. In particular, a resistance to a chemotherapy, such as tamoxifen, is predicted by comparing expressed genes in a patient on the therapy to a patient sensitive to the chemotherapy. In further embodiments, there is an RNA expression profile indicative of tamoxifen resistance in an individual. In additional embodiments, the RNA expression profile comprises DUSP6 EBP50, and/or RhoGDIa.
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