首页> 外国专利> Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents

Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents

机译:通过中断蛋白质成熟来治疗疾病的方法,抑制分子伴侣功能的化合物,例如蛋白质二硫键异构酶或干扰糖基化的化合物,包含它们的药物组合物以及鉴定治疗剂的筛选方法

摘要

A method of treating an infectious disease caused by a pathogen comprising administering to a subject in need thereof an effective amount of one or more compounds that inhibit the function of a molecular chaperone, wherein said compound is other than tizoxanide or nitazoxanide.
机译:一种治疗由病原体引起的感染性疾病的方法,该方法包括向有需要的受试者施用有效量的一种或多种抑制分子伴侣功能的化合物,其中所述化合物不是噻唑烷或硝唑烷。

著录项

  • 公开/公告号US2007015803A1

    专利类型

  • 公开/公告日2007-01-18

    原文格式PDF

  • 申请/专利权人 JEAN-FRANCOIS ROSSIGNOL;

    申请/专利号US20060402259

  • 发明设计人 JEAN-FRANCOIS ROSSIGNOL;

    申请日2006-04-12

  • 分类号A61K31/426;

  • 国家 US

  • 入库时间 2022-08-21 21:04:56

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