首页>
外国专利>
Apparatus and method for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow restrictor
Apparatus and method for coupling microfluidic systems with electrospray ionization mass spectrometry utilizing a hydrodynamic flow restrictor
展开▼
机译:利用流体动力学限流器将微流体系统与电喷雾电离质谱耦合的装置和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A microfluidic device is disclosed wherein a hydrodynamic flow restrictor is positioned in a main channel; a make-up flow channel engages the main channel at a position between the hydrodynamic flow restrictor and an output channel. The hydrodynamic flow restrictor substantially negates a hydrodynamic backpressure in the main channel to the extent that low electroosmotic flow may be utilized in the main channel. Further, a method is disclosed wherein a sample is delivered to the main channel and low EOF drives the sample through the main channel. The method comprises positioning a hydrodynamic flow restrictor in the main channel and delivering a make-up solution via hydrodynamic flow to the main channel at a position between a hydrodynamic flow restrictor and the output channel. The hydrodynamic flow restrictor substantially negates a hydrodynamic backpressure in the main channel to the extent that low electroosmotic flow may be utilized in the main channel.
展开▼