Compounds of the formula (I) for use as an estrogen receptor -β-selective ligand are described wherein: X is O or S; and R1, R3-R6 are as described in the specification. The use of these compounds in treating Alzheimer's disease, anxiety disorders, depressive disorders, osteoporosis, cardiovascular disease, rheumatoid arthritis and prostate cancer is described; as are processes for making them. 展开▼
机译：式（I）的化合物 <图像alt =“嵌入式图像” file =“ US20070208066A1-20070906-C00001.GIF” he =“ 24.98mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 31.67mm“ /> 描述了用作雌激素受体-β-选择性配体的方法，其中： X是O或S; R 1 ，R 3 -R 6 如说明书中所述。描述了这些化合物在治疗阿尔茨海默氏病，焦虑症，抑郁症，骨质疏松症，心血管疾病，类风湿性关节炎和前列腺癌中的用途。以及制作它们的过程。
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