首页> 外国专利> Marker assisted best linear unbiased prediction (ma-blup): software adaptions for large breeding populations in farm animal species

Marker assisted best linear unbiased prediction (ma-blup): software adaptions for large breeding populations in farm animal species

机译:标记辅助的最佳线性无偏预测(ma-blup):适用于农场动物物种大繁殖种群的软件改编

摘要

The invention provides methodologies for improved molecular genetic analysis of individual animals and animal populations. The invention includes methods and systems for identifying those animals in a population that are most likely to heritably pass on desirable traits. Provided are means for evaluating the estimated breeding values and increasing the average genetic merit for animals in a population. For each trait, the instant invention provides methods for evaluating the relative effect of one or more quantitative trait loci (QTL) and three or more molecular genetic markers for each QTL The relationship between these various markers and the pre-selected trait and QTL is calculated, along with the contribution of other factors such as pedigree and known measures with respect to quantitative trait, and these data are used to calculate estimated breeding values for the animals in the herd and to rank the animals according to these estimated breeding values.
机译:本发明提供了用于改进个体动物和动物种群的分子遗传分析的方法。本发明包括用于识别种群中最有可能遗传遗传期望的性状的那些动物的方法和系统。提供了用于评估种群的估计育种值和提高动物平均遗传价值的手段。对于每种性状,本发明提供了用于评估每个QTL的一个或多个定量性状基因座(QTL)和三个或多个分子遗传标记的相对作用的方法。计算了这些各种标记与预先选择的性状和QTL之间的关系。以及其他因素(例如血统和关于定量性状的已知测度)的贡献,这些数据可用于计算畜群中动物的估计繁殖值,并根据这些估计的繁殖值对动物进行排名。

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