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Use of hab18g/cd147 molecule as target for antiviral antagonists and thus obtained antiviral antagonist
Use of hab18g/cd147 molecule as target for antiviral antagonists and thus obtained antiviral antagonist
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机译:使用hab18g / cd147分子作为抗病毒拮抗剂的靶标,从而获得抗病毒拮抗剂
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摘要
The present invention relates to use of HAb18G/CD147 molecule as target for designing antiviral antagonist and the antiviral antagonist designed by using such molecule, especially antagonist against SARS Coronavirus and AIDS virus HIV-1. Antagonist of the present invention includes antibody, polypeptide, immune complex, derivative, small molecule compound and so on, which is able to prevent SARS Coronavirus and AIDS virus (HIV-1) from invading host cell, thereby exerts its antagonistic antiviral effect. It is provided by in vitro experiment that such antagonist has inhibitory effect against SARS Coronavirus and AIDS virus (HIV-1), thus is potential antiviral candidate drug.
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