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Bioreactor mediated recellularization of natural and tissue engineered vascular grafts
Bioreactor mediated recellularization of natural and tissue engineered vascular grafts
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机译:生物反应器介导的天然和组织工程化血管移植物的再细胞化
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摘要
Processes for producing a tissue graft comprising acellularizing or devitalizing a tubular tissue to produce a tissue matrix. The tissue matrix is then populated with at least some viable cells. The processing and the populating steps are performed in a closed system, such as a bioreactor. Tissue grafts produced using the inventive processes may be capable of withstanding physiological stress and strain conditions present at a site into which the tissue graft is implanted.
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