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IG heavy chain, IG kappa, IG lambda biopolymer markers predictive of Alzheimer's disease

机译:IG重链,IGκ,IGλ生物聚合物标志物可预测阿尔茨海默氏病

摘要

The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of at least one disease state relative to recognition of the presence and/or the absence of the biopolymer, predict disease risk assessment, and develop therapeutic avenues against the disease.
机译:本发明涉及将制备步骤与质谱法和飞行时间检测程序结合使用,以使可在特定样品中验证的生物聚合物的多样性最大化。然后参照它们证明至少一种特定疾病状态的能力来查看在此类样品中验证过的生物聚合物。因此,相对于对生物聚合物的存在和/或不存在的识别,诊断医生能够表征至少一种疾病状态的存在,预测疾病风险评估以及开发针对该疾病的治疗途径的能力。

著录项

  • 公开/公告号US7179606B2

    专利类型

  • 公开/公告日2007-02-20

    原文格式PDF

  • 申请/专利权人 GEORGE JACKOWSKI;JOHN MARSHALL;

    申请/专利号US20010993304

  • 发明设计人 JOHN MARSHALL;GEORGE JACKOWSKI;

    申请日2001-11-23

  • 分类号G01N33/53;C07K16/18;

  • 国家 US

  • 入库时间 2022-08-21 21:00:34

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