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COMBINATION THERAPY FOR TREATMENT OF AUTOIMMUNE DISEASES USING B-CELL DEPLETING/IMMUNOREGULATORY ANTIBODY COMBINATION
COMBINATION THERAPY FOR TREATMENT OF AUTOIMMUNE DISEASES USING B-CELL DEPLETING/IMMUNOREGULATORY ANTIBODY COMBINATION
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机译:B细胞耗竭/免疫调节抗体联合治疗自体疾病的联合疗法
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摘要
The present invention concerns treatment of autoimmune diseases with the combination of an immunoregulatory antibody, e.g. an anti-B7.1 or anti-B7.2 or anti-CD40L antibody and at least one B cell depleting antibody, such as CD19, CD20, CD22, CD23, or CD37, wherein such antibodies may be administered separately, or in combination, and in either order, over prolonged periods of time.
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