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HLA-A24 binding peptides of enhancer of zeste homolog 2
HLA-A24 binding peptides of enhancer of zeste homolog 2
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机译:zeste同源物2的增强子的HLA-A24结合肽
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摘要
A cancer antigen peptide comprising an amino acid sequence shown in SEQ ID NO: 1 or 2, or a derivative thereof having the functionally equivalent property is provided. The provided cancer antigen peptide is a partial peptide derived from enhancer of zeste homolog 2, which is capable of binding to HLA-A24 antigen and is recognized by cytotoxic T lymphocytes. The cancer antigen peptide of the invention is useful for treatment and prevention of prostate cancer.
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机译:提供了包含具有SEQ ID NO:1或2所示的氨基酸序列的癌抗原肽或其具有功能上等同的性质的衍生物。所提供的癌症抗原肽是衍生自zeste同系物2的增强子的部分肽,其能够结合HLA-A24抗原并且被细胞毒性T淋巴细胞识别。本发明的癌症抗原肽可用于治疗和预防前列腺癌。
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