serine protease inhibitor compounds, composition, method of inhibiting tf / factor viia, factor xa, thrombin or calicrein activity, method of treating a tf / factor viia, factor xa, thrombin or calicrein mediated dysfunction and method of prevention of thrombosis or treatment of abnormal thrombosis

摘要

SERINE PROTEASE INHIBITORS COMPOSITION, TF / VILA FACTOR ACTIVITY INHIBIT METHOD, FACTOR XA, TROMBINE OR CALICREIN, TREATMENT OF A DIFFORM VILA OR PRETIN FACTOR MEDICATION, TF / VILA FATOR MEDIA TROMBOSIS OR TREATMENT OF ABNORMAL THROMBOSIS Compounds having structure (A) are useful for inhibiting serine protease enzymes such as TF / factor VIa, factor Xa, thrombin and kallikrein. Such compounds may be used in methods of preventing and / or treating coagulation disorders.