Derivatives of N - (1.5 - diphenyl - 1H pyrazole - 3 - YL) sulfonamide with an affinity for the CB1 receptors.

摘要

Derivatives of N - (1.5 - diphenyl - 1H pyrazole - 3 - YL) sulfonamide with an affinity for the CB1 receptors.The present invention relates to compounds corresponding to the formula (1): the process of preparation and application in therapy.In which: sym represents a (C ~ 1 ~ C ~ 6 ~) alkyl; (C ~ 3 ~ C ~ 7 ~) cicloalquila not replaced or replaced one or more times; (C ~ 3 ~ C ~ 7 ~) cicloalquilmetila not replaced or replaced one or more times; fenila not replaced or not replaced or replaced; a benzila Mono - or distarch; a tienila not replaced or replaced; sym represents a hydrogen atom or U.MA (C ~ 1 ~ C ~ 3 ~) alkyl ; sym represents a hydrogen atom or a (C ~ 1 ~ C ~ 5 ~) alkyl; sym sym , , sym sym , , and sym sym each represent independently a hydrogen atom, a halogen atom, and a (C ~ 1 ~ C ~ 7 ~) alkyl, (C ~ 1 ~ C ~ 5 ~) alcu00f3xi, a radical trifluorometi La or a group s (o) n ~ Alq; n represents 0, 1 or 2; alkyl represents a (C ~ 1 ~ C ~ 4 ~) alkyl.The process of preparation and application in therapy.