1,2,3,4-tetrahydro-isoquinoline derivatives, pharmaceutical composition and use of 1,2,3,4-tetrahydro-isoquinoline derivative

摘要

1,2,3,4-TETRA-HYDRO-ISOQUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITION, AND USED OF 1,2,3,4-TETRA-HYDRO-ISOQUIN OLINA Derivatives The invention relates to the novel derivatives of 1,2,3, 4-Tetrahydroisoquinoline of formula (I) wherein R¬ 1¬, R¬ 2¬, R¬ 3¬ and X are as defined in the claims, and their use as active ingredients in the preparation of pharmaceutical compositions . The invention also relates to related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and methods of treatment comprising administering said compounds to a mammal.