首页> 外国专利> use of azd2171 or a pharmaceutically acceptable salt thereof excluding an azd2171 maleate salt and a taxane, pharmaceutical composition, kit, and method for producing antiangiogenic effect and / or reducing vascular permeability in a warm-blooded animal such as as a human being

use of azd2171 or a pharmaceutically acceptable salt thereof excluding an azd2171 maleate salt and a taxane, pharmaceutical composition, kit, and method for producing antiangiogenic effect and / or reducing vascular permeability in a warm-blooded animal such as as a human being

机译:azd2171或其可药用盐(马来酸azd2171盐和紫杉烷类除外)的用途,药物组合物,试剂盒以及在温血动物(例如人)中产生抗血管生成作用和/或降低血管通透性的方法

摘要

USE OF ZD2171 OR A PHARMACEUTICALLY ACCEPTABLE SALT EXCLUDING AN AZD2171 MALEATE SALT AND A TAXAN, PHARMACEUTICAL COMPOSITION, KIT, AND, METHOD FOR THE PRODUCTION OF AN ANTIANGIOGEN EFFECT OF REABILITY AND / OR ANIMAL SINGLE PURPOSE AS A HUMAN The present invention relates to a method for producing an antiangiogenic effect and / or reducing vascular permeability in a warm-blooded animal such as a human being optionally treated with ionizing radiation, particularly a method. for the treatment of a cancer involving a solid tumor comprising administering AZD2171 in combination with a taxane; a pharmaceutical composition comprising AZD2171 and a taxane; a combination product comprising AZD2171 and a taxane for use in a method of treating a human or animal body by therapy; a kit comprising AZD2171 and a taxane; the use of AZD2171 and a taxane in the manufacture of medicament for use in producing an antiangiogenic effect and / or reducing vascular permeability in a warm-blooded animal such as a human being optionally treated with ionizing radiation.
机译:本发明涉及使用ZD2171或不包括马来酸AZD2171的马来酸盐和药学上可接受的盐,药物组合物,试剂盒以及产生抗血管生成素和/或动物目的的抗血管生成素的方法,本发明涉及一种人类方法在温血动物如人中产生抗血管生成作用和/或降低其血管通透性的方法,特别是用电离辐射治疗的方法。用于治疗涉及实体瘤的癌症的方法,包括与紫杉烷类药物联合使用AZD2171;药物组合物,其包含AZD2171和紫杉烷;包含AZD2171和紫杉烷的组合产品,用于通过疗法治疗人体或动物体的方法中;包含AZD2171和紫杉烷的试剂盒; AZD2171和紫杉烷在制造药物中的用途,该药物用于在温血动物(例如可选用电离辐射治疗的人)中产生抗血管生成作用和/或降低血管通透性。

著录项

  • 公开/公告号BRPI0508983A

    专利类型

  • 公开/公告日2007-08-28

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号BR2005PI08983

  • 发明设计人 STEPHEN ROBERT WEDGE;

    申请日2005-03-22

  • 分类号A61K45/06;A61K31/337;A61K31/517;A61P35;

  • 国家 BR

  • 入库时间 2022-08-21 20:59:21

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