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compounds, compositions and methods for stabilizing transthyretin and inhibiting defective duplication of transthyretin

机译：稳定运甲状腺素蛋白和抑制运甲状腺素蛋白复制缺陷的化合物，组合物和方法

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摘要

COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTIRETIN AND INHIBITING DEFECTIVE TRANSTIRETIN DUPLICATION. Compounds, compositions and methods are provided to stabilize transthyretin and to treat, prevent, or ameliorate one or more symptoms of transthyretin-mediated disease. In one embodiment, the compounds are benzoxazoles and related compounds.

机译：用于稳定转铁霉素和抑制缺陷性转铁霉素重复的化合物，组合物和方法。提供化合物，组合物和方法来稳定运甲状腺素蛋白并治疗，预防或改善运甲状腺素蛋白介导的疾病的一种或多种症状。在一实施方案中，所述化合物是苯并恶唑和相关化合物。

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公开/公告号BRPI0510142A

专利类型
公开/公告日2007-10-02

原文格式PDF
申请/专利权人 FOLDRX PHARMACEUTICALS INC.;
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申请/专利号BR2005PI10142
发明设计人 RICHARD LABAUDINIERE;
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申请日2005-05-20
分类号C07D263/56;A61K31/19;A61K31/192;A61K31/195;A61K31/343;A61K31/41;A61K31/4184;A61K31/423;A61K31/428;A61K31/69;A61P3/04;A61P3/10;A61P25/28;C07D263/57;C07D307/91;C07D413/04;C07F5/02;
国家 BR
入库时间 2022-08-21 20:59:18

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