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GPR119 receptor agonists on Methods to increase bone mass and to treat osteoporosis and other conditions characterized by Low bone mass and Combined Therapy related to these agonists

机译:GPR119受体激动剂,涉及增加骨量和治疗骨质疏松症的方法以及其他与这些激动剂有关的低骨量和联合疗法

摘要

The present invention relates to the use of GPR119 receptor agonists for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. The present invention further relates to the use of a GPR119 receptor agonist in combination with a dipeptidyl peptidase IV (DPP-IV) inhibitor for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. A GPR119 receptor agonist and the combination of a GPR119 receptor agonist and a DPP-IV inhibitor promote bone formation in an individual.
机译:本发明涉及GPR119受体激动剂在治疗或预防以骨量低为特征的疾病如骨质疏松症和增加个体骨量​​中的用途。本发明进一步涉及GPR119受体激动剂与二肽基肽酶IV(DPP-IV)抑制剂联合用于治疗或预防以骨量低为特征的疾病如骨质疏松症和增加个体骨量​​的用途。 。 GPR119受体激动剂以及GPR119受体激动剂和DPP-IV抑制剂的组合可促进个体的骨形成。

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