Tetrahydroisoquinoline TETRAGIDROBENZAZEPINOVYE AND DERIVATIVES (OPTIONS), pharmaceutical compositions and pharmaceutical kits, medicinal and reference instruments for the test-systems based on them, methods of treatment and prevention of diseases in which the down-regulation of a favorable or inhibiting the expression or function of IGF-1 Receptor

摘要

The compounds of formula (I) are synthesized in which R, R, R have the meanings as described, and U, V and W, respectively, can be CR ', CR' and CR ', (with the definitions of R', R ' and R 'again, as described) or may mean N. It is shown that they down-regulate or inhibit the expression or function of the IGF-1 receptor.