首页> 外国专利> ANTIARRHYTHMIC, ANTIFBIRILLATORY, AND DEFIBRILLATORY PHARMACEUTICAL COMPOSITIONS CONTAINING DIBENZOAZEPINES AND DIBENZODIAZEPINES AND SAME SUCH NOVEL COMPOUNDS

ANTIARRHYTHMIC, ANTIFBIRILLATORY, AND DEFIBRILLATORY PHARMACEUTICAL COMPOSITIONS CONTAINING DIBENZOAZEPINES AND DIBENZODIAZEPINES AND SAME SUCH NOVEL COMPOUNDS

机译:抗心律失常,抗纤颤和去纤颤的药物组合物,包含二苯甲嗪和二苯并二氮杂卓以及相同的新型化合物

摘要

A compound having a general formula (II) wherein RSUB1 /SUBis saturated or unsaturated alkyl, amino-alcohol, diamino, cycloalkyl, and C(-O)(CHSUB2/SUB)SUBn/SUBNR'R'', (CHSUB2/SUB)SUBn/SUBCHOHCHSUB2/SUBNR'R'', wherein n is an integer, RSUBQ, R/SUBSUBT/SUB, R', and R'' are each independently a hydrogen, halogen, hydroxyl, saturated, unsaturated, aliphatic, or branched alkyl, substituted or unsubstituted (CHSUB2/SUB)SUBm/SUB-(hetero)aryl, and sulfonylamide; q and r are each an integer independently selected from 1-4; and pharmaceutically acceptable salts thereof, and the new therapeutic uses thereof and similar compounds as defibrillating, and/or anti-fibrillatory, and/or anti-arrhythmic and/or anti-ischemic drugs.
机译:具有通式(II)的化合物,其中R 1 是饱和或不饱和烷基,氨基醇,二氨基,环烷基和C(-O)(CH 2 n NR'R'',(CH 2 n CHOHCH 2 NR'R'',其中n是一个整数,R Q,R T ,R'和R''各自独立地是氢,卤素,羟基,饱和,不饱和,脂族或支链烷基,取代或未取代的(CH 2 m -(杂)芳基和磺酰胺; q和r分别是独立地选自1-4的整数;及其药学上可接受的盐,以及其新的治疗用途以及与类似化合物的除纤颤和/或抗纤颤和/或抗心律不齐和/或抗缺血药物。

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