A METHOD OF PRODUCING CELL FREE IMMUNOGEN/VACCINE AND METHOD OF PRODUCING DIAGNOSTIC KIT FOR EARLY DETECTION OF CANCERS

摘要

A cell free preparations of tumor antigen adapted for immunotherapy of cancer and/or prophylactic vaccine thereof for destroying cancer cell as soon as these appear in the body. Also discloses is a diagnostic kit and a method of early detection and treatment of cancer involving the aforesaid cell free preparation of tumor antigen. The developed cell free immunogen preparation/vaccine comprise cell free form of tumor antigen covalently bound with antigen presenting fraction of major histocompatiability complex (MHC) which is immunologically antigenic and capable of sensitizing lymphocytes and at the same time free from any of the cell surface makers which may cause auto-immune diseases in the immunized subjects. The diagnostic kit involving the above cell free preparations of tumor antigen provide for a simple, effective and early detection of cancer and a method for carrying out such detection of cancer. The cell free preparation is also directed to save in the method of treatment for making all the cancer cells in the body vulnerable to destructible by an activated immune surveillance system in the host and as a prophylactic vaccination adapted to destroy cancer cells as soon as these appear in the body.