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PROCESS FOR PRODUCING ENANTIOPURE B-AMINO ACID DERIVATIVES, AND ENANTIOPURE B-AMINO ACID DERIVATIVES
PROCESS FOR PRODUCING ENANTIOPURE B-AMINO ACID DERIVATIVES, AND ENANTIOPURE B-AMINO ACID DERIVATIVES
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机译:制备对映体B-氨基酸衍生物和对映体B-氨基酸衍生物
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摘要
Process for producing enantiopure β-amino acid derivatives corresponding to general formula (I) Rl-NZ-CHR2-CH2-COOR3 (I) in which Rl and R2 independently denote organic residues optionally forming a cyclic substituent, R3 denotes H or an organic residue, and Z represents H or an amino function-protecting group, comprising a step in which a mixture of enantiomers of a compound corresponding to general formula (II) Rl-NZ-CHR2-CH2-COOR4 (II) in which Rl, R2 and Z are as defined for formula (I), and R4 is an organic residue, is subjected to hydrolysis in the presence of a lipase. No figure.
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