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SYSTEM, METHODS AND REAGENTS FOR THE DETECTION OF BIOLOGICAL AND CHEMICAL AGENTS USING DYNAMIC SURFACE GENERATION AND IMAGING
SYSTEM, METHODS AND REAGENTS FOR THE DETECTION OF BIOLOGICAL AND CHEMICAL AGENTS USING DYNAMIC SURFACE GENERATION AND IMAGING
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机译:动态表面生成和成像检测生物化学试剂的系统,方法和试剂
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摘要
Techniques for the sensitive detection of analytes which combine the benefits of solution/suspension phase assay formats and the simplicity of solid phase/lateral flow assays are described. The assays can be performed in the solution/suspension phase using magnetic microspheres as a solid support. Subsequently a magnetic separation can be performed to separate the bound analyte from the remainder of the solution. After a wash step, the fluorescence signal can be directly read from the magnetic particle surface. Portable biodetection systems which employ fluorescent polymer superquenching and methods for detecting bioagents therewith are also described.
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