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A METHOD FOR THE PREPARATION OF 3S-2(2S*, 3S*),3A,4aB,8aB-N-(1,1-DIMETHYLETHYL)DECAHYDRO-2-2-HYDROXY-3-(3-HYDROXY-2-METHYLBEENZOYL)AMINO-4-(PHENYLTHIO)BUTYL-3-ISOQUINOLINECARBOXAMIDE
A METHOD FOR THE PREPARATION OF 3S-2(2S*, 3S*),3A,4aB,8aB-N-(1,1-DIMETHYLETHYL)DECAHYDRO-2-2-HYDROXY-3-(3-HYDROXY-2-METHYLBEENZOYL)AMINO-4-(PHENYLTHIO)BUTYL-3-ISOQUINOLINECARBOXAMIDE
The present invention discloses a method for the preparation of an oxazoline from a tetrahydrofuran which comprises converting tetrahydrofuran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir.
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