1-'(3R)-A MINO-4(2-FLUORO-PHENYL)-BUTYL -PYRROLIDINE-(2R)- CARBOXILIC ACID-BENZYL AMINE DERIVATIVES AND RELATED COMPOUNDS AS DIPEPTIDYL-PEPTIDASE IV (DPP-IV) INHIBITORS FOR THE TREATMENT OF TYPE 2 DIABETES MELLITUS

摘要

The invention relates to compounds of Formula(I) wherein, R'9, Z, n, X, A, and Rb have the meaning as cited in the description and the claims. Said compounds are useful as DPP-JV inhibitors. The invention also relates to the preparation of such compounds as well as production and use thereof as medicament for the treatment of type 2 diabetes mellitus, obesity and lipid disorders.