A NOVEL PROCESS OF PREPARATION OF MOUTH DISPERSIBLE TABLET OF ONDANSETRONE HCL DIHYDRATE

摘要

A novel process of preparing a mouth dispersible ondansetrone Hcl dihydrate tablet comprising the following steps, Mixing an active ingredients of ondansetrone Hcl dihydrate 5 mg / unit dose , with other excipients like sweetening agent lactose 634 mg / unit dose , starch 164.5 mg/ Unit dose, aspartame 8 mg /unit dose , and sodium saccharine 6 mg /unit dose; flavourants 13.5 mg /unit dose ; free soluble compound anhydrous dextrose 20 mg/unit dose , and lactose ; paste of starch and polyvinyl pyrrolidine K-30 12 mg / unit dose as binder and followed by granulating and lubricating .