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Coated microgranules containing a gastric proton pump inhibitor with two hydrophobic materials, free from alkali and any ionic surfactant
Coated microgranules containing a gastric proton pump inhibitor with two hydrophobic materials, free from alkali and any ionic surfactant
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机译:含有胃质子泵抑制剂和两种疏水性物质的涂层微粒,不含碱和任何离子表面活性剂
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摘要
A pharmaceutical formulation of a gastric proton pump inhibitor, with the exception of omeprazole, is disclosed. The formulation is in the form of microgranules insoluble in gastric fluid having improved stability over time. The formulation comprises several hydrophobic substances chosen in order to increase the stability of the active principle while obtaining the desired dissolution profile.
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