Pharmaceutical ingredients including soffeni

摘要

The substance refers to a pharmaceutical compound containing 4 - {4 - {3 - (4-chloro-3-trifluoride) urea] phenyl methylamide as an active agent. Pyridine-2-carbohydrates or sorafenib (Bay 43-9006) as an active agent, as a stable polymorphine I, is preferred in the form of anhydrides (p-toluene) salt at least 40% by weight. Microcrystalline cellulose, 0% to 60% by weight; restless, 0% to 15% by weight; polymer, such as hypnosis, 0% to 15% by weight; lubricant, such as magnesium stearate, 0% to 2% by weight;And a surface activity, such as laurilsulfato sodium, in the range of 0% to 5% by weight. He also mentioned a preparatory process This component is a pure oral pharmacology form, like a long-term release of compression agent, the active agent is microparticle, is an inhibition of pentagonal hormone, so it is useful in the treatment of malignant diffusive disorders such as cancer.