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METHOD FOR PRODUCING A HETEROLOGOUS SECRETED PROTEIN FROM CHINESE HAMSTER OVARY CELLS GROWN ON MICROCARRIERS
METHOD FOR PRODUCING A HETEROLOGOUS SECRETED PROTEIN FROM CHINESE HAMSTER OVARY CELLS GROWN ON MICROCARRIERS
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机译:从微载体上生长的中国仓鼠卵巢细胞生产异源分泌分泌蛋白的方法
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摘要
The present invention relates to a method for producing a heterologous secreted protein from transformed CHO cells grown on microcarriers in a serum-free cell culture medium. This method avoids a production lag phase when switching from a serum-containing to a serum-free environment, a problem observed in the mammalian adherent cell culture production of secreted proteins.
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