Pharmaceutical preparation comprising an active agent of topiramate, process for forming and use thereof

摘要

A process for forming a pharmaceutical preparation comprising: a) preparing core particles comprising an active agent of topiramate, b) drying the core particles from step a) to form dried core particles, c) coating the dried core particles from step b) with a taste masking mixture to form coated particles and d) drying the coated particles from step c) to form the pharmaceutical preparation, wherein the amount of taste masking mixture ranges from 7 to 15 % by weight of the pharmaceutical preparation.