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SYSTEMS FOR THE PRESENTATION OF CLASS II MHC ANTIGENES AND METHOD FOR THE ACTIVATION OF CD4 + T-LYMPHOCYTES
SYSTEMS FOR THE PRESENTATION OF CLASS II MHC ANTIGENES AND METHOD FOR THE ACTIVATION OF CD4 + T-LYMPHOCYTES
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机译:呈递II类MHC抗原的系统和激活CD4 + T淋巴细胞的方法
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摘要
The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules with one or more accessory molecules. The matrices are used to activate naive CD4+ T cells as well as shift the ongoing activation state into a preferred differentiated population of either Th1 or Th2 cells.
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