USE OF 2,5-DIHYDROXIBENCENOSULFONIC ACID, IN THE MANUFACTURE OF APPLICATION MEDICINES IN THE TREATMENT OF ANGIODEPENDENT DISEASES.

摘要

Use of 2,5-dihydroxybenzenesulfonic acid, in the manufacture of medicinal products for the treatment of angiodependent diseases. The invention covers the application of this compound and, particularly of its calcium and potassium salts, in the treatment of angiodependent diseases and that show a decrease in apoptosis, such as cancer and psoriasis. The invention shows the antiproliferative, antimigratory, antiangiogenic and proapoptotic capacity of this family of compounds in non-quiescent cells. It also reflects the potentiating effect of these compounds on known cytostatic drugs in the treatment of tumors, specifically on gliomas. Finally, the therapeutic efficacy of these compounds, based on the combination of their antiproliferative, antiangiogenic and proaptotic abilities, in the treatment of chronic psoriatic plaques is revealed.