Stabilized, amorphous calcium atorvastatin, useful as antihypercholesterolemic agent, is non-hygroscopic and stable under normal conditions of relative humidity and temperature

摘要

Stabilized calcium atorvastatin (A) is a non-hygroscopic material of water content 7-9.5wt.% that remains stable at relative humidity (RH) 55-65% at ambient temperature and/or at RH 70-80% at above ambient temperature, for at least 90 days. An independent claim is included for a method for preparing (A). ACTIVITY : Antilipemic. No details of tests for antilipemic activity are given. MECHANISM OF ACTION : None given.