PROCESS OF INHIBITION OF THE GENES TRANSCRIPTION.

摘要

THE INVENTION REFERS TO INHIBITION OF TRANSCRIPTION OF GENES IN HIGH EUCARIOTIC CELLS THROUGH INHIBITION OF ACTIVATION OF NF - {SUB.K} B, BEING TREATED CELLS WITH SUBSTANCES THAT SPECIFICALLY INHIBIT, DIRECTLY OR INDIRECTLY, PROPOSED IT { SUB.K} B - {AL}. THE INVENTION REFERS TO A METHOD OF SCREENING SUBSTANCES THAT INHIBIT ACTIVATION NF - {SUB.K} B THROUGH PROTEOLITIC DECOMPOSITION INHIBITION OF I {SUB.K} B - {AL}, AS WELL AS THE USE OF SUCH SUBSTANCES FOR TREATMENT OF PATHOLOGICAL CONDITIONS ATTRIBUTABLE TO THE EXPRESSION OF UNWANTED GENES, CONTROLLED BY NF - {SUB.K} B.