INHIBITION OF THE GROWTH OF CHRONIC MYELOGEN LEUKEMIA CELLS BY OLIGODESOXI-NUCLEOTID ANTISENTIDO LIPOSOMALES DIRECTED TO GRB2.

摘要

IN THE PRESENT INVENTION NEW COMPOSITIONS AND PROCEDURES ARE PRESENTED TO BE USED IN THE TREATMENT OF CANCER, SPECIFICALLY IN THE TREATMENT OF CHRONIC MIELOGEN LEUKEMIA (CML). THE COMPOSITIONS CONTAIN OLIGONUCLEOTIDES HYBRIDIZED TO NUCLEIC ACIDS GRB2 AND CRK1, WHOSE GENETIC PRODUCTS KNOW THAT THEY INTERACT WITH THE TUMORIGENA BRC - ABL PROTEIN. USED ONLY ONLY, UNITED BETWEEN YEAR AND EVEN NEXT TO OLIGONUCLEOTIDOS ANTISENTIDO DIRECTED TO NUCLEIC ACIDS BCR ABL, THESE COMPOSITIONS INHIBIT THE PROLIFERATION OF CANCEROSE CELLS OF THE CML.