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Microarrays to carry out proteomic analysis.

机译:微阵列进行蛋白质组学分析。

摘要

An array of agents binding proteins stably attached to the surface of a solid support, said array comprising: a solid substrate having a substantially planar aluminum, the aluminum coated with a coating of silicon dioxide, wherein the silicon dioxide coating has a thickness of about 20 nm to about 90 nm and is capable of enhancing amplification of a fluorescent signal; a set of binding agents different proteins bound to said substrate, each of said binding agents proteins comprising a segment joined anchor stably to the substrate surface, a segment of peptidomimetic protein binding, and linker segment connecting and separating the anchoring segments and peptidomimetic segments
机译:稳定结合到固体支持物表面上的结合蛋白质的试剂阵列,所述阵列包括:具有基本平坦的铝的固体基质,所述铝涂覆有二氧化硅涂层,其中所述二氧化硅涂层的厚度为约20大约90nm,并且能够增强荧光信号的放大;一组与所述底物结合的不同蛋白质的结合剂,每个所述结合剂蛋白质包括一个稳定地连接至底物表面的锚定片段,一个拟肽蛋白质结合片段以及连接和分离锚定片段和拟肽片段的接头片段

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