SINGLE DOMAIN LIGANDS, RECEPTORS COMPRISING SAID LIGANDS, METHODS FOR THEIR PRODUCTION, AND USE OF SAID LIGANDS AND RECEPTORS

摘要

The present invention relates to single domain ligandsderived from molecules in the immunoglobulin (Ig)superfamily, receptors comprising at least one such ligand,methods for cloning, amplifying and expressing DNA sequencesencoding such ligands, preferably using the polymerase chainreaction, methods for the use of said DNA sequences in theproduction of Ig-type molecules and said ligands orreceptors, and the use of said ligands or receptors intherapy, diagnosis or catalysis.